Last Updated on February 25, 2022 by Allison Price
Although the drug initially decreased airway sensitivity in the beginning, it seems to have a reduced effectiveness over time.
Clenbuterol is a beta-2-adrenoceptor antagonist and the FDA’s only approved medication for horses suffering from reversible asthma. It is also commonly used to treat horses suffering from inflammatory airway disease (IAD), recurrent bronchospasm (RAO) or heaves. It is frequently administered to racehorses during the racing season. However, its long-term effects remain unclear.
A team of researchers from the University of Pennsylvania School of Veterinary Medicine’s New Bolton Center conducted a study to this end. They found that while clenbuterol initially reduces airway sensitivity for inhaled histamines but that long-term usage can lead to decreased bronchoprotective effectiveness.
Rose NolenWalston, DVM assistant professor in PennVet’s Department of Clinical Sciences, stated that “many horses, especially race horses,” receive clenbuterol daily.
I’m Allison, born and raised in San Diego California, the earliest memory I have with horses was at my grandfather’s farm. I used to sit at the stable as a kid and hang out with my Papa while he was training the horses. When I was invited to watch a horse riding competition, I got so fascinated with riding!